The mechanism of the irreversible inhibition of rat-liver monoamine oxidase by iproniazid (marsilid).

نویسنده

  • A N DAVISON
چکیده

Gould, R. G., Lotz, L. V. & Lilly, E. M. (1956). Biochemical Problems of Lipids, p. 353. Ed. by Popjik, G. & Le Breton, F. London: Butterworths. Green, B., Lowe, J. S. & Morton, R. A. (1955). Biochem. J. 61, 447. Green, C. (1955). Ph.D. Thesis: University of Liverpool. Hahn, L. & Hevesy, G. (1939). Nature, Lond., 144, 72. Hemandez, H. H., Chaikoff, I. L., Dauben, W. G. & Abraham, S. (1954). J. biol. Chem. 206, 757. Hewitt, W. (1954). Quart. J. Micr. Sci. 95, 153. Kenny, A. P. (1952). Biochem. J. 52, 611. Kim, K. S. & Ivy, I. C. (1952). Amer. J. Physiol. 171, 302. Moore, P. R. & Baumann, C. A. (1952). J. biol. Chem. 195, 615. Mueller, J. H. (1916). J. biol. Chem. 27, 463. Peterson, D. W. (1951). Proc. Soc. exp. Biol., N. Y., 78, 143. Schneider, W. C. & Hogeboom, G. H. (1950). J. biol. Chem. 183, 123. Schotz, M. C., Rice, L. I. & Alfin-Slater, R. B. (1953). J. biol. Chem. 204, 19. Schwenk, E. & Werthessen, N. T. (1952). Arch. Biochem. Biophys. 40, 334. Sj6strand, F. S. & Rhodin, J. (1953). Exp. Cell Res. 4, 426. Spiro, M. J. & McKibbin, J. M. (1956). J. biol. Chem. 219, 643. Swanson, M. A. & Artom, C. (1950). J. biol. Chem. 187,281. Swell, L., Field, H. & Treadwell, C. R. (1955). Proc. Soc. Exp. Biol., N. Y., 87, 216.

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عنوان ژورنال:
  • The Biochemical journal

دوره 67 2  شماره 

صفحات  -

تاریخ انتشار 1957